megatomi.com Can Be Fun For Anyone
megatomi.com Can Be Fun For Anyone
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Rapidly obtain sections as skinny or thick as your software necessitates, with out stressing about getting rid of or distorting valuable tissue samples.
Megatome is a vibrating microtome made to segment a broad variety of samples, from organoids and biopsy samples to expanded rodent brains and intact human organs. With significant blade vibrating frequency and minimized blade deflection, Megatome permits high-throughput tissue sectioning with uniform surface profile, in addition to nominal tissue damage and information loss.
Antibodies might consider weeks to diffuse through only a few millimeters of tissue, that has a steep labeling gradient from area to Main.
Megatome is created for precision: the blade vibrates at an increased frequency and bigger amplitude selection than other microtomes, and incorporates a one of a kind deflection Command system.
SE employs a rotational electrical area to disperse highly electromobile molecules (such as antibodies or surfactant micelles) all over a porous sample without the need of detrimental electrically billed constructions within the tissue. This allows two-4 day clearing of intact organs,
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Megatome is really a novel microtome which allows for prime-precision sectioning of a wide range of tissue samples – from organoids, to arrays of animal organs, to intact human Mind hemispheres – with negligible tissue hurt and information decline.
eFLASH is actually a rapid tissue labeling procedure that permits for uniform full-organ staining in 20 rounds of labeling.
The SmartSPIM gentle sheet microscope presents unparalleled resolution and acquisition velocity all through intact tissue volumes, though its modular design and style helps you to update and customise personal factors.
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Protect avoids the variability of hydrogel embedding and the information loss from PFA preservation, safeguarding specimens for various rounds of processing.
Leverage the Obvious+ tissue clearing system, along with eFLASH and patented stochastic megatomi.com electrotransport technologies, to swiftly obvious and label full organs. Key highlights and attributes incorporate:
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